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Bio-Medical research in several areas. Born in Odessa, USSR, June 28, 1958. Married, 2 sons EDUCATION 2009 Continuing Education Courses for Therapists. 2009 Continuing Education Courses for Diagnostic Medical Sonographers. 1996 Ph.D., Developmental Biology, Koltzov Inst. of Developmental Biology, Russian Academy of Sciences. 1984 Residency, Endocrinology, Moscow Medical Inst., Moscow City Hospital N 52. 1983 M.D ., Therapeutics, Moscow State University of Medicine and Dentistry. EMPLOYMENT/RESIDENCIES/POSTDOCTORAL 4/2013-present Prokhorov General Physics Institute of the Russian Academy of Sciences. 06/10-03/2013 Lab. for Regenerative Medicine of Moscow State University , Moscow, Russia. 05/04-05/2010 Research Instructor, Division of Rheumatology & Immunology, Medical University of South Carolina. Professor Maria Trojanowska. 03/03-04/2004 Postdoctoral Fellow, Cell Biology and Anatomy Dept., Medical University of South Carolina. Associate Prof. Andy Wessels. 03/99-02/2003 Postdoctoral Fellow, Ophthalmology Dpt., Storm Eye Inst. Medical University of South Carolina. Associate Prof. J.X. Ma. 11/96-02/1999 Postdoctoral Associate, N.K. Koltzov Inst. of Developmental Biology, Russia Academy of Sciences, Moscow, Russia. Prof. V.I.Mitashov. 09/91-10/1991 Visiting Scientist, University of Cologne, Cologne, Germany. Dr. H.-J. Anton 09/89-11/96 Post-Graduate Student, Inst. of Developmental Biology, Russian Academy of Sciences. Moscow. Prof. V.I.Mitashov. Ph.D. Thesis: The Role of Several Growth Factors in the Regeneration of Eye Tissues and Limbs in Amphibians. 09/86-07/89 Trainee, Inst. of Developmental Biology, Academy of Sciences of USSR. Moscow. Prof. V.I.Mitashov. 09/84-08/86 Residency. Emergency Doctor. Moscow Station of Urgent Medical Aid. 07/83-07/84 Residency. Endocrinology. Moscow City Hospital N 52. Dr. A.Ya. Sklyannik. 0/82-083 Undergraduate Student, Moscow Medical Inst., Student Scientific Society in Embryology and Histology. Prof. Podkopayev. 0/81-0/83 Undergraduate Student, Moscow Medical Inst., Inst. of Transplantology and Artificial Organs, Student Scientific Society in Endocrinology. Prof. V.N. Blumkin TEACHING EXPERIENCE 2001 The MCBP Teaching Techniques Course (spring semester), Medical University of South Carolina 1998-9 “Principles of Physiology" and "General Ecology" lecture courses for students, Tsiolkovsky Institute of Aircraft Engineering Moscow, Russia 1998 "Developmental Biology: Limb Development and Regeneration," Moscow Medical Institute. 1995 Multi-lecture courses "State of Art in Biology," Russian Society of Nature Researchers. AWARDS AND PROFESSIONAL SOCIETIES. 1999 Prize from the State Publishing House "Nauka" for the best scientific publication 1999 Member of the Association for Research in Vision and Ophthalmology (ARVO), USA. 1989 Member of the Russian Society of Nature Researches. INVITED SPEAKER AND PRESENTATIONS 2004 MBA Meeting. San Diego, USA 2004 ARVO Meeting, Fort Lauderdale, USA 2000 ARVO Meeting, Fort Lauderdale, USA 1999 FASEB summer Research Conference 1998 All-Russian Conference on the Regeneration Problems, Moscow, Russia 1998 4th International Conference on the Limb Development and Regeneration, Sun Valley, Idaho, USA 1996 Conference of International Association for research on regeneration, Cologne, Germany 1995 European Developmental Biology Congress 1994 European conference "Mechanisms of onthogenesis and evolution," Uzkoe, Moscow, Russia 1990 First European conference on tissue and post-traumatic regeneration, Geneva, Switzerland 1990 International Congress of Eye Research, Helsinki, Finland 1990 NATO ARW "Developmental patterning of the vertebrate limb," Santander, Spain 1988 Soviet-Finnish Symposium on Developmental Biology, Tashkent, USSR. 1988 All-Union workshop on Morphogenetic Active Factors, Puschino, USSR. PUBLICATIONS More than 30 publications and presentations in peer review journals and conferences, the most significant being: Alexey V. Orlov, Sergey L. Znoyko, Vladimir R. Cherkasov, Maxim P. Nikitin, and Petr I. Nikitin. Multiplex Biosensing Based on Highly Sensitive Magnetic Nanolabel Quantification: Rapid Detection of Botulinum Neurotoxins A, B, and E in Liquids. Anal. Chem., 2016, 88 (21), pp 10419–10426. DOI: 10.1021/acs.analchem.6b02066 Orlov A.V., Bragina V.A., Znoyko S.L., Shevchenko K.G. Biosensors based on magnetic nanolabels: optimization with spectral interferometry and highly-sensitive electronic registration. IEEE Хplore, 2016, P. S2-38. DOI:10.1109/LO.2016.7550005 AlexeyV.Orlov a, MaximP.Nikitin a,b,c, VeraA.Bragina a, SergeyL.Znoyko a, Marina N.Zaikina a, TatianaI.Ksenevich a, BorisG.Gorshkov a, PetrI.Nikitin. A new real-time method for investigation of affinity properties and binding kinetics of magnetic nanoparticles. Journal of Magnetism and Magnetic Materials. 380 (2015) 231–235. Alexey V. Orlov, Maxim P. Nikitin, Vera A. Bragina, Sergey L. Znoyko, Marina N. Zaikina, Tatiana I. Ksenevich, Boris G. Gorshkov, Petr I. Nikitin. A new real-time method for investigation of affinity properties and binding kinetics of magnetic nanoparticles. Journal of Magnetism and Magnetic Materials. In Press, doi:10.1016/j.jmmm.2014.10.019 Markiewicz M, Znoyko S, Stawski L, Ghatnekar A, Gilkeson G, Trojanowska M. A Role for Estrogen Receptor-α and Estrogen Receptor-β in Collagen Biosynthesis in Mouse Skin. J Invest Dermatol. 2012 Aug 16. doi: 10.1038/jid.2012.264. PMID: 22895361 Tourkina E., M. Bonner, J.Oates, A.Hofbauer, M. Richard, S. Znoyko, R.P Visconti, J. Zhang, C.M Hatfield, R.M Silver and S. Hoffman Altered monocyte and fibrocyte phenotype and function in scleroderma interstitial lung disease: reversal by caveolin-1 scaffolding domain peptide. Fibrogenesis Tissue Repair. 2011 Jul 1;4(1):15 Tourkina E, Richard M, Oates J, Hofbauer A, Bonner M, Gööz P, Visconti R, Zhang J, Znoyko S, Hatfield CM, Silver RM, Hoffman S. Caveolin-1 regulates leucocyte behaviour in fibrotic lung disease. Ann Rheum Dis. 2010 Jun; 69(6):1220-6. Epub 2010 Apr 21.PMID: 20410070 Chen Y, Znoiko S, Degrip WJ, Crouch RK, Ma JX. Salamander Blue-sensitive Cones Lost During Metamorphosis. Photochem Photobiol. 2008 Mar 7; PMID: 18331398 M. Markiewicz, Y. Asano, S. Znoyko, Y. Gong, D.K. Watson and M. Trojanowska. Distinct effects of gonadectomy in male and female mice on collagen fibrillogenesis in the skin. Journal of Dermatological Science Volume 47, Issue 3, September 2007, Pages 217-226 Znoiko SL, Rohrer B, Lu K, Lohr HR, Crouch RK, Ma JX. Downregulation of cone-specific gene expression and degeneration of cone photoreceptors in the Rpe65-/- mouse at early ages. Invest Ophthalmol Vis Sci. 2005 Apr;46(4):1473-9 Rohrer B., Goletz P., Znoiko S., Ablonczy Z., Ma J.-X., Redmond M., and R. Crouch. Correlation of regenarable opsin with rod Erg signal in RPE65+/- mice during development and aging. Investigative Ophthalology & Visual Science. 2003. 44(1): 310-5. Darden AG, Wu BX, Znoiko SL, Hazard ES 3rd, Kono M, Crouch RK, Ma JX. A novel Xenopus SWS2, P434 visual pigment: structure, cellular location, and spectral analyses. Mol Vis. 2003 May 16;9:191-9. Ma J-X, Znoiko S., Othersen K., Ryan J., Das J., Isayma T., Kono M., Oprian D., Corson D., Cornwall M., Cameron D., Harosi F., Makino C., and R. Crouch. A visual pigment expressed in both rod and cone photoreceptors. Neuron. 2001. 32(3): 451-461. Znoiko S., Crouch R., Moiseyev G., and J-X Ma. Identification of RPE65 protein in mammalian cone photoreceptors. Investigative Ophthalology and Visual Science. 2001. 43(5):1604-1609. Ryan J, Znoiko S, Xu L. Crouch R., and J-X Ma. Salamander rods and cones contain distinct transducin alpha subunits. Visual Neuroscience. 2000. 17, 847-854. Liinnola R.J., Werner L., Pandey S.K., Escobar-Gomez M., Znoiko S.L., Apple D.J. Adhesion of fibronectin, vitronectin, laminin, and collagen type IV to intraocular lens materials in pseudophakic human autopsy eyes. Part 2. Explanted intraocular lenses. Journal of Cataract and Refractive Surgery. 2000. 26(12):1807-1818. Znoiko S.L. A "packaging" model of limb development. In: Development Patterning of the Vertebrate Limb. Plenum Press. New York, 1991. - P. 261- 263. Znoiko S.L. The morphogenesis of the regenerating limb (RL) (The packaging model). In "1st European conference on tissue and post-traumatic regeneration", Geneva, 1990, p.37.